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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10928 | Cytochalasin A | HIV Protease | |
Cytochalasin A is a cell-permeable fungal toxin and is an oxidized derivative of cytochalasin B. Cytochalasin A is an inhibitor of HIV-1 protease (IC50 = 3 μM), inhibits actin polymerization and interferes with microtubu... | |||
T7097 | Cytochalasin B | Phomin | Arp2/3 Complex |
Cytochalasin B is a mycotoxin binding to the barbed end of actin filaments. It can disrupt the formation of actin polymers (Kd: 1.4-2.2 nM for F-actin). | |||
T21513 | Cytochalasin H | (16-Benzyl-5,12-dihydroxy-5,7,14-trimethyl-13-methylidene-18-oxo-17-azatricyclo[9.7.0.01,15]octadeca-3,9-dien-2-yl) acetate | MMP |
Cytochalasin H ((16-Benzyl-5,12-dihydroxy-5,7,14-trimethyl-13-methylidene-18-oxo-17-azatricyclo[9.7.0.01,15]octadeca-3,9-dien-2-yl) acetate) is a potent inhibitor of actin incorporation into filaments. | |||
T13630 | Cytochalasin C | Others | |
Cytochalasin C is a cell-permeable fungal toxin that can induce the formation of nuclear sticks. Cytochalasin C is 10 times less toxic than cytochalasin D in mice. | |||
T82628 | Cytochalasin N | ||
Cytochalasin N, derived from the endophytic fungus Phomopsis sp.CIB-109 [1], is a cytorelaxin. | |||
T82629 | Cytochalasin K | ||
Cytochalasin K (Compound 7) is a cytochalasin known to inhibit wheat root elongation, exhibiting an IC50 value of 22.58 μM [1]. | |||
T15039 | Cytochalasin E | Others | |
Cytochalasin E is a potent actin depolymerization agent and an epoxide containing Aspergillus-derived fungal metabolite. Cytochalasin E also inhibits angiogenesis and tumor growth. It binds and caps the barbed end of act... | |||
T82627 | Cytochalasin O | ||
Cytochalasin O (compound 13), a secondary metabolite produced by the phytopathogenic fungus P. sp. CIB-109 [1], is characterized by its bioactive properties. | |||
TN2408 | Evofolin B | Cannabinoid Receptor | |
Evofolin B is a natural compound isolated from the stem bark of Zanthoxylum ailanthoides. Evofolin B has an inhibitory effect on the superoxide anion produced by human neutrophils in response to formyl-L-methionine-L-leu... | |||
TN2767 | 2'-Hydroxygenistein | Antifection | |
2'-Hydroxygenistein has antifungal activity, dimerization of it causes a remarkable increase of antifungal activity. It shows significant concentration-dependent inhibitory effects on the release of beta-glucuronidase an... | |||
T11042 | Dihydrocytochalasin B | Others | |
Dihydrocytochalasin B (H2CB) is a cell division inhibitor that changes the morphology of cells, similar to cytochalasin B. Does not inhibit glucose transport. Dihydrocytochalasin B (H2CB) disrupts the structure of actin ... | |||
T37477 | L-858,051 (hydrochloride) | ||
L-858,051 is a water-soluble analog of forskolin , a cell-permeant activator of adenylate cyclase. L-858,051 activates adenylate cyclase (EC50 = 3 μM), inhibits glucose transport, and blocks cytochalasin B binding in rat... | |||
T36005 | 1-Oleoyl-2-Palmitoyl-rac-glycerol | ||
1-Oleoyl-2-palmitoyl-rac-glycerol (1,2-OP) is a diacylglycerol containing oleic acid at the sn-1 position and palmitic acid at the sn-2 position. It enhances the inhibition of superoxide anion production by cytochalasin ... | |||
T36355 | Sydowinin B | ||
Sydowinin B is a xanthone polyketide that has been found inA. sydowiiand has immunosuppressant activity.1It inhibits LPS- or concanavalin A-induced proliferation of isolated mouse splenic lymphocytes (IC50s = 19.2 and 20... | |||
TN2766 | 2'-Hydroxydaidzein | Cannabinoid Receptor , Antioxidant | |
2'-Hydroxydaidzein is an isoflavonoid phytonutrient found in plant species, when a natural compound. 2'-Hydroxydaidzein has antioxidant activity, driven mainly by o-hydrogen bond dissociation enthalpy (BDE) and hydrogen ... |